Pseudomonas stutzeri DSM 10701, PSJM300_00750

Gene Feature Overview

Strain	Pseudomonas stutzeri DSM 10701 GCF_000279165.1|latest
Locus Tag	PSJM300_00750
Name
Replicon	chromosome
Genomic location	161203 - 162654 (- strand)

Cross-References

RefSeq	YP_006522592.1
GI	397685273
Entrez	13326396
INSDC	AFN76234.1
NCBI Locus Tag	PSJM300_00750
UniParc	UPI00026D85CE
UniProtKB Acc	I6ZW41
UniProtKB ID	I6ZW41_PSEST
UniRef100	UniRef100_I6ZW41
UniRef50	UniRef50_Q92JG3
UniRef90	UniRef90_I6ZW41

Product

Feature Type	CDS
Coding Frame	1
Product Name	NAD(P)(+) transhydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	1.65
Kyte-Doolittle Hydrophobicity Value	0.690
Molecular Weight (kDa)	50689.4
Isoelectric Point (pI)	7.77

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name	Source Accession	Source DB	Version	Target Accession	Target Description	Percent Identity	Alignment Length	E-Value
2'-Monophosphoadenosine 5'-Diphosphoribose	DB03461	DrugBank	5.1.4	P0C188	NAD(P) transhydrogenase subunit beta	59.0	483	9.1e-144

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 305 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000195 (532 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSJM300_00750 Search term: NAD(P)(+) transhydrogenase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000499639 nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863] E-value: 1.9e-96 Percent Identity: 45.2
Ensembl 110, assembly GRCh38.p14	ENSP00000499527 nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863] E-value: 1.9e-96 Percent Identity: 45.2
Ensembl 110, assembly GRCh38.p14	ENSP00000499670 nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863] E-value: 1.9e-96 Percent Identity: 45.2
Ensembl 110, assembly GRCh38.p14	ENSP00000264663 nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863] E-value: 1.9e-96 Percent Identity: 45.2
Ensembl 110, assembly GRCh38.p14	ENSP00000343873 nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863] E-value: 1.9e-96 Percent Identity: 45.2
Ensembl 110, assembly GRCh38.p14	ENSP00000499494 nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863] E-value: 1.9e-96 Percent Identity: 45.2
Ensembl 110, assembly GRCh38.p14	ENSP00000426343 nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863] E-value: 1.9e-96 Percent Identity: 45.2
Ensembl 110, assembly GRCh38.p14	ENSP00000499249 nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863] E-value: 1.9e-96 Percent Identity: 45.2
Ensembl 110, assembly GRCh38.p14	ENSP00000499281 nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863] E-value: 1.9e-96 Percent Identity: 45.2
Ensembl 110, assembly GRCh38.p14	ENSP00000499611 nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863] E-value: 1.9e-96 Percent Identity: 45.2

References