Pseudomonas aeruginosa 2192, PA2G_00356

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_00356
Name
Replicon	chromosome
Genomic location	374666 - 376099 (- strand)

Cross-References

RefSeq	ZP_04933053.1
GI	254239731
NCBI Locus Tag	PA2G_00356
UniProtKB Acc	A3LD77
UniProtKB ID	A3LD77_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	multidrug transporter MatE
Synonyms
Evidence for Translation
Charge (pH 7)	12.55
Kyte-Doolittle Hydrophobicity Value	0.622
Molecular Weight (kDa)	50.9
Isoelectric Point (pI)	9.99

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name	Definition	Accession	Model Type (?)	SNP	Cutoff	Bit Score	Percent Identity	CARD Version
PmpM	PmpM is a multidrug efflux pump belonging to the MATE family of Pseudomonas aeruginosa. PmpM is an H+ drug antiporter and is the first reported case of an H+ coupled efflux pump in the MATE family. PmpM confers resistance to fluoroquinolones, fradiomycin, benzalkonium chloride, chlorhexidine gluconate, ethidium bromide, tetraphenylphosphonium chloride (TPPCl), and rhodamine 6G. [PMID:14679249]	ARO:3004077	protein homolog model		Strict	926.0	99.79	3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001295 (965 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_00356 Search term: multidrug transporter MatE

Human Homologs

References