Pseudomonas mendocina NK-01, MDS_4759

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas mendocina NK-01
GCF_000204295.1|latest
Locus Tag
MDS_4759
Name
Replicon chromosome
Genomic location 5211274 - 5212452 (- strand)

Cross-References

RefSeq YP_004382542.1
GI 330505673
Entrez 10459541
INSDC AEB60790.1
NCBI Locus Tag MDS_4759
UniParc UPI000206DD21
UniProtKB Acc F4DRS0
UniProtKB ID F4DRS0_PSEMN
UniRef100 UniRef100_F4DRS0
UniRef50 UniRef50_Q92947
UniRef90 UniRef90_Q4KKG4

Product

Feature Type CDS
Coding Frame 1
Product Name
acyl-CoA dehydrogenase domain-containing protein
Synonyms
Evidence for Translation
Charge (pH 7) -3.52
Kyte-Doolittle Hydrophobicity Value -0.184
Molecular Weight (kDa) 43107.9
Isoelectric Point (pI) 6.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
1-(1,4-dimethyl-1,2,3,4-tetrahydroquinoxalin-6-yl)methanamine DB08685 DrugBank 5.1.4 Q3JP94 Glutaryl-CoA dehydrogenase 84.6 395 1.4e-193

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 469 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000438 (528 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: MDS_4759

Human Homologs

Ensembl 110, assembly GRCh38.p14
glutaryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4189]
E-value: 1.5e-144
Percent Identity: 64.3
Ensembl 110, assembly GRCh38.p14
glutaryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4189]
E-value: 1.5e-144
Percent Identity: 64.3

References

No references are associated with this feature.