Pseudomonas protegens Pf-5, PFL_1069 (lepA)

Gene Feature Overview

Strain	Pseudomonas protegens Pf-5 GCF_000012265.1|latest
Locus Tag	PFL_1069
Name	lepA
Replicon	chromosome
Genomic location	1220090 - 1221889 (+ strand)

Cross-References

RefSeq	YP_258200.2
GI	346642758
Entrez	3477480
INSDC	AAY90356.2
NCBI Locus Tag	PFL_1069
UniParc	UPI00006A785B
UniProtKB Acc	Q4KHT3
UniProtKB ID	LEPA_PSEF5
UniRef100	UniRef100_Q4KHT3
UniRef50	UniRef50_O67618
UniRef90	UniRef90_Q87XF8

Product

Feature Type	CDS
Coding Frame	1
Product Name	GTP-binding protein LepA
Synonyms
Evidence for Translation
Charge (pH 7)	-12.57
Kyte-Doolittle Hydrophobicity Value	-0.105
Molecular Weight (kDa)	66388.6
Isoelectric Point (pI)	5.53

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000741 (533 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PFL_1069 Search term: lepA Search term: GTP-binding protein LepA

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000281543 GTP binding elongation factor GUF1 [Source:HGNC Symbol;Acc:HGNC:25799] E-value: 9.6e-175 Percent Identity: 49.8

References