Pseudomonas protegens CHA0, PFLCHA0_c58220 (coaD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas protegens CHA0 - Assembly GCF_000397205.1
GCF_000397205.1|latest
Locus Tag
PFLCHA0_c58220
Name
coaD
Replicon chromosome
Genomic location 6467532 - 6468011 (+ strand)

Cross-References

RefSeq YP_008003054.1
GI 501683228
EC Number 2.7.7.3
Entrez 15563739
NCBI Locus Tag PFLCHA0_c58220

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphopantetheine adenylyltransferase CoaD
Synonyms
Evidence for Translation
Charge (pH 7) 2.19
Kyte-Doolittle Hydrophobicity Value -0.023
Molecular Weight (kDa) 17.8
Isoelectric Point (pI) 8.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5TS2 TRANSFERASE 10/27/16 Crystal structure of a phosphopantetheine adenylyltransferase (CoaD, PPAT) from Pseudomonas aeruginosa bound to dephospho coenzyme A Pseudomonas aeruginosa (strain LESB58) 2.3 X-RAY DIFFRACTION 92.4
3X1M TRANSFERASE 11/24/14 Crystal structure of Phosphopantetheine adenylyltransferase/PPAT from Pseudomonas aeruginosa with CoA Pseudomonas aeruginosa 2192 2.5 X-RAY DIFFRACTION 92.5
3X1J TRANSFERASE 11/19/14 Crystal Structure of Phosphopantetheine adenylyltransferase (PPAT/CoaD) with AcCoA from Pseudomonas aeruginosa Pseudomonas aeruginosa 2192 2.334 X-RAY DIFFRACTION 92.5
3X1K TRANSFERASE 11/20/14 crystal structure of Phosphoapantetheine adenylyltransferase PPAT/CoaD with AMP-PNP from Pseudomonas aerugonosa Pseudomonas aeruginosa 2192 2.547 X-RAY DIFFRACTION 92.5
5X6F TRANSFERASE 02/21/17 Crystal structure of Phosphopantetheine adenylyltransferase from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.593 X-RAY DIFFRACTION 92.5
4RUK TRANSFERASE 11/20/14 crystal structure of Phosphoapantetheine adenylyltransferase PPAT/CoaD with CoA and pyrophosphate from Pseudomonas aeruginosa Pseudomonas aeruginosa 2192 2.2 X-RAY DIFFRACTION 92.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 578 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000354 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PFLCHA0_c58220
Search term: coaD

Human Homologs

References

No references are associated with this feature.