Pseudomonas poae RE_1-1-14, H045_18615

Gene Feature Overview

Strain	Pseudomonas poae RE*1-1-14 GCF_000336465.1|latest
Locus Tag	H045_18615
Name
Replicon	chromosome
Genomic location	4253040 - 4254293 (- strand)

Cross-References

RefSeq	YP_007399281.1
GI	447918713
EC Number	2.1.2.1
Entrez	14505513
INSDC	AGE27785.1
NCBI Locus Tag	H045_18615
UniParc	UPI0002A79392
UniProtKB Acc	M4KAR7
UniProtKB ID	M4KAR7_9PSED
UniRef100	UniRef100_M4KAR7
UniRef50	UniRef50_P9WGI9
UniRef90	UniRef90_Q48CP3

Product

Feature Type	CDS
Coding Frame	1
Product Name	serine hydroxymethyltransferase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.30
Kyte-Doolittle Hydrophobicity Value	-0.069
Molecular Weight (kDa)	44.5
Isoelectric Point (pI)	6.65

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 654 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003094 (1150 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: H045_18615 Search term: serine hydroxymethyltransferase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000452419 serine hydroxymethyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10852] E-value: 3.5e-91 Percent Identity: 46.8
Ensembl 110, assembly GRCh38.p14	ENSP00000406881 serine hydroxymethyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10852] E-value: 3.5e-91 Percent Identity: 46.8
Ensembl 110, assembly GRCh38.p14	ENSP00000333667 serine hydroxymethyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10852] E-value: 3.5e-91 Percent Identity: 46.8
Ensembl 110, assembly GRCh38.p14	ENSP00000413770 serine hydroxymethyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10852] E-value: 3.5e-91 Percent Identity: 46.8

References