Pseudomonas aeruginosa LESB58, PALES_58851 (dsbA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest |
| Locus Tag |
PALES_58851
|
| Name |
dsbA
|
| Replicon | chromosome |
| Genomic location | 6516857 - 6517492 (- strand) |
Cross-References
| RefSeq | YP_002443462 |
| GI | 218894592 |
| Entrez | 7179469 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
thiol:disulfide interchange protein DsbA
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -2.38 |
| Kyte-Doolittle Hydrophobicity Value | -0.064 |
| Molecular Weight (kDa) | 23.4 |
| Isoelectric Point (pI) | 6.40 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 2MBT | OXIDOREDUCTASE | 08/03/13 | NMR study of PaDsbA | Pseudomonas aeruginosa | NOT | SOLUTION NMR | 100.0 |
| 4ZL7 | OXIDOREDUCTASE | 05/01/15 | Crystal structure of Pseudomonas aeruginosa DsbA E82I: Crystal I | Pseudomonas aeruginosa | 1.922 | X-RAY DIFFRACTION | 98.4 |
| 5TLQ | OXIDOREDUCTASE | 10/11/16 | Model structure of the oxidized PaDsbA1 and 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine complex | Pseudomonas aeruginosa | NOT | SOLUTION NMR | 100.0 |
| 3H93 | TRANSCRIPTION REGULATOR | 04/29/09 | Crystal Structure of Pseudomonas aeruginosa DsbA | Pseudomonas aeruginosa PAO1 | 1.501 | X-RAY DIFFRACTION | 99.0 |
| 4ZL8 | OXIDOREDUCTASE | 05/01/15 | Crystal structure of Pseudomonas aeruginosa DsbA E82I: Crystal II | Pseudomonas aeruginosa | 1.395 | X-RAY DIFFRACTION | 98.4 |
| 5DCH | OXIDOREDUCTASE | 08/24/15 | Crystal structure of Pseudomonas aeruginosa DsbA E82I in complex with MIPS-0000851 (3-[(2-METHYLBENZYL)SULFANYL]-4H-1,2,4-TRIAZOL-4-AMINE) | Pseudomonas aeruginosa | 1.447 | X-RAY DIFFRACTION | 98.4 |
| 4ZL9 | OXIDOREDUCTASE | 05/01/15 | Crystal structure of Pseudomonas aeruginosa DsbA E82I: Crystal III | Pseudomonas aeruginosa | 1.7 | X-RAY DIFFRACTION | 98.4 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 149 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG005029 (534 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PALES_58851
Search term: dsbA
Search term: thiol:disulfide interchange protein DsbA
|
Human Homologs
References
No references are associated with this feature.