Pseudomonas aeruginosa PACS2, A0K_RS09760
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PACS2
GCF_000168335.1|latest |
| Locus Tag |
A0K_RS09760
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 2042658 - 2044091 (- strand) |
Cross-References
| RefSeq | ZP_01364730.1 |
| GI | 107100812 |
| NCBI Locus Tag | A0K_RS09760 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
multidrug transporter MatE
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 12.55 |
| Kyte-Doolittle Hydrophobicity Value | 0.632 |
| Molecular Weight (kDa) | 50.8 |
| Isoelectric Point (pI) | 9.99 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| PmpM | PmpM is a multidrug efflux pump belonging to the MATE family of Pseudomonas aeruginosa. PmpM is an H+ drug antiporter and is the first reported case of an H+ coupled efflux pump in the MATE family. PmpM confers resistance to fluoroquinolones, fradiomycin, benzalkonium chloride, chlorhexidine gluconate, ethidium bromide, tetraphenylphosphonium chloride (TPPCl), and rhodamine 6G. [PMID:14679249] | ARO:3004077 | protein homolog model | Perfect | 927.2 | 100.0 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG001295 (965 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: A0K_RS09760
Search term: multidrug transporter MatE
|
Human Homologs
References
No references are associated with this feature.