Pseudomonas aeruginosa PAO1, PA0153 (pcaH)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0044248	cellular catabolic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0015976	carbon utilization	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Molecular Function	GO:0005506	iron ion binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF49482	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0019619	3,4-dihydroxybenzoate catabolic process	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR02422	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0018578	protocatechuate 3,4-dioxygenase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR02422	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF49482	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006725	cellular aromatic compound metabolic process	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00775	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003824	catalytic activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00775	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008199	ferric iron binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00775	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae01120	Microbial metabolism in diverse environments	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Aromatic compound catabolism		ECO:0000037 not_recorded
KEGG	pae01220	Degradation of aromatic compounds	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00362	Benzoate degradation	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY	protocatechuate degradation II (ortho-cleavage pathway)	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF12391	Protocatechuate 3,4-dioxygenase beta subunit N terminal	IPR024756	Protocatechuate 3,4-dioxygenase beta subunit, N-terminal	12	43	3.6E-14
PANTHER	PTHR33711:SF8	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN	-	-	2	239	0.0
SUPERFAMILY	SSF49482	Aromatic compound dioxygenase	IPR015889	Intradiol ring-cleavage dioxygenase, core	11	238	1.44E-74
Gene3D	G3DSA:2.60.130.10	Aromatic compound dioxygenase	IPR015889	Intradiol ring-cleavage dioxygenase, core	2	239	5.5E-85
TIGRFAM	TIGR02422	protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit	IPR012785	Protocatechuate 3,4-dioxygenase, beta subunit	17	238	1.5E-105
PANTHER	PTHR33711	DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED	-	-	2	239	0.0
Pfam	PF00775	Dioxygenase	IPR000627	Intradiol ring-cleavage dioxygenase, C-terminal	48	229	3.3E-58

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.