Pseudomonas aeruginosa PAO1, PA0170 (siaC)

Annotation Updates

Date	Description	Acknowledgements
Nov 20, 2022	New gene name: siaC. New product name: SiaC. New product name synonym: putative anti-sigma factor antagonist. New product name confidence: Class 1. New comment: The phosphorylation status of T68 of the SiaC protein is balanced by the phosphatase activity of SiaA (PA0172) and kinase activity of SiaB (PA0171)[PMID:33156827];The SiaABC threonine phosphorylation pathway controls aggregate/biofilm formation in response to carbon availability (glucose, succinate, ethanol, 2,3-butanediol)[PMID:33156827];The SiaC protein shares structural similarities with anti-sigma factor antagonists (PDB-ID: 6K4F)[PMID:33156827]. New PMID: 33156827.	Janosch Klebensberger, University of Stuttgart, Institute of Technical Biochemistry, Stuttgart, Germany