Pseudomonas aeruginosa PAO1, PA0172 (siaA)

Annotation Updates

Date	Description	Acknowledgements
Nov 20, 2022	New comment: SiaA is a functional Mg2+/Mn2+-dependent protein-phosphatase (PP2C-type) with activity towards the phosphorylated threonine T68 of SiaC (PA0170) [PMID:33156827];The SiaABC threonine phosphorylation pathway controls aggregate/biofilm formation in response to carbon availability (glucose, succinate, ethanol, 2,3-butanediol)[PMID:33156827];The SiaA-PP2C domain is arranged as a homodimer in the crystal asymmetric unit (PDB-ID: 6K4E) and its phosphatase activity can be inhibited by fumonisin B1[PMID:33156827]. New PMID: 33156827.	Janosch Klebensberger, University of Stuttgart, Institute of Technical Biochemistry, Stuttgart, Germany
Aug 25, 2011	New product name: SiaA. New gene name: siaA. New product name confidence: Class 1. New comment : Involved in surfactant-induced (SDS) aggregation.. New function class: Motility & Attachment. New PubMed reference: 17686022. New PubMed reference: 19638175.	Janosch Klebensberger, Universitat Konstanz, Germany
Jan 20, 2017	New PubMed ID: 26955366. New comment: Involved in postranscriptional regulation of CupA fimbriae via transcriptional activation of rsmZ.	Janosch Klebensberger, University of Stuttgart, Institute of Technical Biochemistry, Stuttgart