Pseudomonas aeruginosa PAO1, PA0219

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0219
Name
Replicon chromosome
Genomic location 247219 - 248709 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_248910.1
GI 15595416
Affymetrix PA0219_at
Entrez 879237
GenBank AAG03608.1
INSDC AAG03608.1
NCBI Locus Tag PA0219
protein_id(GenBank) gb|AAG03608.1|AE004460_1|gnl|PseudoCAP|PA0219
TIGR NTL03PA00220
UniParc UPI00000C4FA2
UniProtKB Acc Q9I6R9
UniProtKB ID Q9I6R9_PSEAE
UniRef100 UniRef100_U8MJD1
UniRef50 UniRef50_C9YAW5
UniRef90 UniRef90_A0A077JPA1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable aldehyde dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -10.41
Kyte-Doolittle Hydrophobicity Value -0.036
Molecular Weight (kDa) 53.6
Isoelectric Point (pI) 5.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 604 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000218 (393 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0219

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 8.3e-108
Percent Identity: 44.9
Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 8.3e-108
Percent Identity: 44.9
Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 8.3e-108
Percent Identity: 44.9

References

Cloning an Escherichia coli gene encoding a protein remarkably similar to mammalian aldehyde dehydrogenases.
Heim R, Strehler EE
Gene 1991 Mar 1;99(1):15-23
PubMed ID: 1840553