Pseudomonas aeruginosa PAO1, PA0413 (chpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00072
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Motility & Attachment Other PAO1 genes in this class
Two-component regulatory systems Other PAO1 genes in this class
Chemotaxis Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Two-component System ECO:0000037
not_recorded
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Pilin biosynthesis ECO:0000037
not_recorded
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Chemotaxis ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 864 960 4.0594E-10
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 2039 2175 1.8E-16
MobiDBLite mobidb-lite consensus disorder prediction - - 987 1035 -
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 2035 2176 1.3E-22
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1522 1651 3.6E-27
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1185 1312 8.6E-14
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1364 1457 6.7E-14
PANTHER PTHR43395 SENSOR HISTIDINE KINASE CHEA - - 1756 2471 0.0
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1670 1774 5.48041E-13
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 864 989 4.6E-27
Coils Coil Coil - - 1370 1390 -
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2136 2154 1.5E-10
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1184 1304 1.91E-15
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1989 2175 1.0E-52
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1524 1623 4.7E-14
Coils Coil Coil - - 1889 1909 -
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 7 130 1.83E-23
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1362 1492 5.1E-29
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1041 1132 2.06508E-5
SMART SM01231 H_kinase_dim_2 IPR004105 Histidine kinase CheA-like, homodimeric domain 1851 1990 1.3E-11
SMART SM00260 chew_2 IPR002545 CheW-like domain 2168 2318 2.0E-34
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1663 1796 3.3E-23
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 14 137 1.3E-11
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 864 961 3.8E-6
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1669 1766 6.4E-4
CDD cd16916 HATPase_CheA-like - - 1998 2173 1.18824E-83
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1362 1484 1.83E-27
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2160 2173 1.5E-10
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 2353 2464 3.07577E-30
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1522 1620 5.79877E-15
Gene3D G3DSA:3.40.50.2300 - - - 2353 2472 5.3E-40
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1043 1129 2.5E-11
Gene3D G3DSA:2.30.30.40 SH3 Domains - - 2256 2316 2.9E-19
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 2181 2320 1.2E-22
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1362 1459 6.6E-7
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1035 1170 3.3E-18
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1041 1144 0.49
MobiDBLite mobidb-lite consensus disorder prediction - - 565 618 -
Coils Coil Coil - - 1752 1779 -
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2080 2094 1.5E-10
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 2350 2469 3.98E-36
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1362 1460 3.42739E-15
FunFam G3DSA:3.30.565.10:FF:000016 Chemotaxis protein CheA, putative - - 1991 2175 1.7E-60
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 864 994 4.5E-28
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 10 98 3.0E-8
Coils Coil Coil - - 232 252 -
MobiDBLite mobidb-lite consensus disorder prediction - - 658 679 -
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 866 953 1.6E-13
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 2353 2465 1.6E-27
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1671 1764 3.9E-15
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1522 1619 0.0095
SUPERFAMILY SSF50341 CheW-like IPR036061 CheW-like domain superfamily 2175 2314 1.7E-21
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 2351 2464 2.9E-37
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1670 1778 4.19E-20
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1041 1164 4.84E-19
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 433 556 1.94E-14
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1992 2173 7.99E-36
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1522 1644 1.83E-26

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.