Pseudomonas aeruginosa PAO1, PA0424 (mexR)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0045892	negative regulation of transcription, DNA-templated	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	10671465	Reviewed by curator
Biological Process	GO:0045892	negative regulation of transcription, DNA-templated	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	10671465	Reviewed by curator
Biological Process	GO:0034763	negative regulation of transmembrane transport	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	8878574	Reviewed by curator
Molecular Function	GO:0000976	transcription regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	11208776	Reviewed by curator
Biological Process	GO:0050709	negative regulation of protein secretion	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	8878574	Reviewed by curator
Biological Process	GO:0034763	negative regulation of transmembrane transport	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	8878574	Reviewed by curator
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00598	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006355	regulation of transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00598	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae01501	beta-Lactam resistance	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00598	Bacterial regulatory protein MarR family signature	IPR000835	MarR-type HTH domain	118	138	9.7E-7
PRINTS	PR00598	Bacterial regulatory protein MarR family signature	IPR000835	MarR-type HTH domain	88	104	9.7E-7
Gene3D	G3DSA:1.10.10.10	-	IPR036388	Winged helix-like DNA-binding domain superfamily	9	142	3.7E-37
FunFam	G3DSA:1.10.10.10:FF:001107	Multidrug resistance operon repressor MexR	-	-	9	142	2.7E-92
SUPERFAMILY	SSF46785	Winged helix DNA-binding domain	IPR036390	Winged helix DNA-binding domain superfamily	6	138	1.67E-29
SMART	SM00347	marrlong4	IPR000835	MarR-type HTH domain	28	128	9.2E-30
PANTHER	PTHR35790	HTH-TYPE TRANSCRIPTIONAL REGULATOR PCHR	-	-	11	140	1.1E-21
PRINTS	PR00598	Bacterial regulatory protein MarR family signature	IPR000835	MarR-type HTH domain	69	84	9.7E-7
Pfam	PF01047	MarR family	IPR000835	MarR-type HTH domain	35	92	5.4E-17

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.