Pseudomonas aeruginosa PAO1, PA0493

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0493
Name
Replicon chromosome
Genomic location 552746 - 552994 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249184.1
GI 15595690
Affymetrix PA0493_at
DNASU PaCD00006206
Entrez 878648
GenBank AAG03882.1
INSDC AAG03882.1
NCBI Locus Tag PA0493
protein_id(GenBank) gb|AAG03882.1|AE004486_11|gnl|PseudoCAP|PA0493
TIGR NTL03PA00494
UniParc UPI00000C5089
UniProtKB Acc Q9I625
UniProtKB ID Q9I625_PSEAE
UniRef100 UniRef100_W0YLW4
UniRef50 UniRef50_D8ITF2
UniRef90 UniRef90_W0YLW4

Product

Feature Type CDS
Coding Frame 1
Product Name
probable biotin-requiring enzyme
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -6.53
Kyte-Doolittle Hydrophobicity Value 0.105
Molecular Weight (kDa) 8.5
Isoelectric Point (pI) 4.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 453 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000481 (327 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0493

Human Homologs

References

Structure of the carboxy-terminal fragment of the apo-biotin carboxyl carrier subunit of Escherichia coli acetyl-CoA carboxylase.
Yao X, Wei D, Soden C Jr, Summers MF, Beckett D
Biochemistry 1997 Dec 9;36(49):15089-100
PubMed ID: 9398236