Pseudomonas aeruginosa PAO1, PA0502

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0502
Name
Synonym: bioH
Replicon chromosome
Genomic location 562006 - 562728 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_249193.1
GI 15595699
Affymetrix PA0502_at
Entrez 878654
GenBank AAG03891.1
INSDC AAG03891.1
NCBI Locus Tag PA0502
protein_id(GenBank) gb|AAG03891.1|AE004487_5|gnl|PseudoCAP|PA0502
TIGR NTL03PA00503
UniParc UPI00000C5092
UniProtKB Acc Q9I616
UniProtKB ID Q9I616_PSEAE
UniRef100 UniRef100_W0YLX3
UniRef50 UniRef50_Q4K4T4
UniRef90 UniRef90_A0A077JKE7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable biotin biosynthesis protein bioH
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -19.63
Kyte-Doolittle Hydrophobicity Value -0.075
Molecular Weight (kDa) 26.5
Isoelectric Point (pI) 4.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 113 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000489 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0502

Human Homologs

References

Nucleotide sequence of the bioH gene of Escherichia coli.
O'Regan M, Gloeckler R, Bernard S, Ledoux C, Ohsawa I, Lemoine Y
Nucleic Acids Res 1989 Oct 11;17(19):8004
PubMed ID: 2678009