Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0510
|
Name |
nirE
Synonym: nirE |
Replicon | chromosome |
Genomic location | 572583 - 573422 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_249201.1 |
GI | 15595707 |
Affymetrix | PA0510_at |
Entrez | 881871 |
GenBank | AAG03899.1 |
INSDC | AAG03899.1 |
NCBI Locus Tag | PA0510 |
protein_id(GenBank) | gb|AAG03899.1|AE004488_3|gnl|PseudoCAP|PA0510 |
TIGR | NTL03PA00511 |
UniParc | UPI00000D4275 |
UniProtKB Acc | G3XD80 |
UniProtKB ID | G3XD80_PSEAE |
UniRef100 | UniRef100_W0YLY2 |
UniRef50 | UniRef50_W6LVC5 |
UniRef90 | UniRef90_V6A922 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
NirE
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 0.26 |
Kyte-Doolittle Hydrophobicity Value | 0.159 |
Molecular Weight (kDa) | 29.7 |
Isoelectric Point (pI) | 7.09 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
2YBQ | TRANSFERASE | 03/09/11 | The x-ray structure of the SAM-dependent uroporphyrinogen III methyltransferase NirE from Pseudomonas aeruginosa in complex with SAH and uroporphyrinogen III | PSEUDOMONAS AERUGINOSA | 2 | X-RAY DIFFRACTION | 100.0 |
2YBO | TRANSFERASE | 03/08/11 | The x-ray structure of the SAM-dependent uroporphyrinogen III methyltransferase NirE from Pseudomonas aeruginosa in complex with SAH | PSEUDOMONAS AERUGINOSA | 2 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 537 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000495 (353 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0510
Search term: nirE
Search term: NirE
|
The Pseudomonas aeruginosa nirE gene encodes the S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase required for heme d(1) biosynthesis.
Storbeck S, Walther J, Müller J, Parmar V, Schiebel HM, Kemken D, Dülcks T, Warren MJ, Layer G
FEBS J 2009 Oct;276(20):5973-82
PubMed ID: 19754882
|
Gene cluster for dissimilatory nitrite reductase (nir) from Pseudomonas aeruginosa: sequencing and identification of a locus for heme d1 biosynthesis.
Kawasaki S, Arai H, Kodama T, Igarashi Y
J Bacteriol 1997 Jan;179(1):235-42
PubMed ID: 8982003
|