Pseudomonas aeruginosa PAO1, PA0649 (trpG)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0000162	tryptophan biosynthetic process	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	2153661	Reviewed by curator
Molecular Function	GO:0004049	anthranilate synthase activity	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	2153661	Reviewed by curator

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other PAO1 genes in this class Amino acid biosynthesis and metabolism Other PAO1 genes in this class Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Folate biosynthesis		ECO:0000037 not_recorded
KEGG	pae01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Phenylalanine, tyrosine and tryptophan biosynthesis		ECO:0000037 not_recorded
PseudoCyc	TRPSYN-PWY	L-tryptophan biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	PWY-6661	4-hydroxy-2(1H)-quinolone biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Ubiquinone biosynthesis		ECO:0000037 not_recorded
KEGG	pae02025	Biofilm formation - Pseudomonas aeruginosa	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	ALL-CHORISMATE-PWY	superpathway of chorismate metabolism	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	PWY-6660	2-heptyl-3-hydroxy-4(1H)-quinolone biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae00400	Phenylalanine, tyrosine and tryptophan biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	COMPLETE-ARO-PWY	superpathway of aromatic amino acid biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01230	Biosynthesis of amino acids	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae02024	Quorum sensing	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01130	Biosynthesis of antibiotics	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
FunFam	G3DSA:3.40.50.880:FF:000003	Anthranilate synthase component II	-	-	1	194	1.0E-90
PRINTS	PR00096	Glutamine amidotransferase superfamily signature	-	-	74	85	1.4E-13
PANTHER	PTHR43418	MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED	-	-	2	193	6.3E-86
PRINTS	PR00099	Carbamoyl-phosphate synthase protein GATase domain signature	-	-	44	58	1.0E-5
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	169	182	2.3E-37
Gene3D	G3DSA:3.40.50.880	-	IPR029062	Class I glutamine amidotransferase-like	1	193	3.0E-62
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	47	56	2.3E-37
SUPERFAMILY	SSF52317	Class I glutamine amidotransferase-like	IPR029062	Class I glutamine amidotransferase-like	1	192	1.34E-54
PRINTS	PR00096	Glutamine amidotransferase superfamily signature	-	-	169	182	1.4E-13
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	74	85	2.3E-37
Pfam	PF00117	Glutamine amidotransferase class-I	IPR017926	Glutamine amidotransferase	4	191	2.8E-55
PRINTS	PR00099	Carbamoyl-phosphate synthase protein GATase domain signature	-	-	74	90	1.0E-5
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	2	16	2.3E-37
CDD	cd01743	GATase1_Anthranilate_Synthase	IPR006221	Anthranilate synthase/para-aminobenzoate synthase like domain	2	190	1.59035E-112
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	99	107	2.3E-37
PRINTS	PR00096	Glutamine amidotransferase superfamily signature	-	-	47	56	1.4E-13
NCBIfam	TIGR00566	JCVI: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	IPR006221	Anthranilate synthase/para-aminobenzoate synthase like domain	1	191	7.1E-87
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	119	131	2.3E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.