Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
---|---|---|---|---|---|---|
Biological Process | GO:0000162 | tryptophan biosynthetic process | Inferred from Mutant Phenotype | ECO:0000016 loss-of-function mutant phenotype evidence |
22555873 | Reviewed by curator |
Molecular Function | GO:0004425 | indole-3-glycerol-phosphate synthase activity | Inferred from Direct Assay | ECO:0000314 direct assay evidence used in manual assertion |
22555873 | Reviewed by curator |
Molecular Function | GO:0004425 | indole-3-glycerol-phosphate synthase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF00218
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
|
Database | Xref | Pathway | Version | Evidence | PMID |
---|---|---|---|---|---|
PseudoCyc | COMPLETE-ARO-PWY | superpathway of aromatic amino acid biosynthesis | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
KEGG | pae01230 | Biosynthesis of amino acids | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
PseudoCyc | TRPSYN-PWY | L-tryptophan biosynthesis | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
PseudoCyc | ALL-CHORISMATE-PWY | superpathway of chorismate metabolism | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
KEGG | pae01130 | Biosynthesis of antibiotics | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
KEGG | pae01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
KEGG | pae00400 | Phenylalanine, tyrosine and tryptophan biosynthesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
PseudoCAP | Phenylalanine, tyrosine and tryptophan biosynthesis |
ECO:0000037
not_recorded |
|||
KEGG | pae01110 | Biosynthesis of secondary metabolites | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
---|---|---|---|---|---|---|---|
PANTHER | PTHR22854 | TRYPTOPHAN BIOSYNTHESIS PROTEIN | IPR045186 | Indole-3-glycerol phosphate synthase | 5 | 265 | 4.6E-86 |
Gene3D | G3DSA:3.20.20.70 | Aldolase class I | IPR013785 | Aldolase-type TIM barrel | 1 | 271 | 2.5E-106 |
CDD | cd00331 | IGPS | IPR013798 | Indole-3-glycerol phosphate synthase domain | 43 | 263 | 2.84342E-113 |
Pfam | PF00218 | Indole-3-glycerol phosphate synthase | IPR013798 | Indole-3-glycerol phosphate synthase domain | 7 | 263 | 3.3E-102 |
Hamap | MF_00134_B | Indole-3-glycerol phosphate synthase [trpC]. | IPR013798 | Indole-3-glycerol phosphate synthase domain | 5 | 265 | 36.629158 |
FunFam | G3DSA:3.20.20.70:FF:000024 | Indole-3-glycerol phosphate synthase | - | - | 1 | 267 | 6.7E-97 |
SUPERFAMILY | SSF51366 | Ribulose-phoshate binding barrel | IPR011060 | Ribulose-phosphate binding barrel | 14 | 265 | 2.0E-86 |