Pseudomonas aeruginosa PAO1, PA0652 (vfr)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0009405	pathogenesis	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	14977975	Reviewed by curator
Biological Process	GO:0043902	positive regulation of multi-organism process	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	9190808	Reviewed by curator
Biological Process	GO:0006355	regulation of transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:PF13545	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003677	DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF13545	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae02024	Quorum sensing	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae02025	Biofilm formation - Pseudomonas aeruginosa	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00034	CRP bacterial regulatory protein HTH signature	IPR012318	Crp-type HTH domain	186	201	3.3E-9
PRINTS	PR00034	CRP bacterial regulatory protein HTH signature	IPR012318	Crp-type HTH domain	170	186	3.3E-9
FunFam	G3DSA:1.10.10.10:FF:000006	cAMP-activated global transcriptional regulator CRP	-	-	143	211	1.6E-41
Gene3D	G3DSA:1.10.10.10	-	IPR036388	Winged helix-like DNA-binding domain superfamily	143	211	1.9E-39
Pfam	PF00027	Cyclic nucleotide-binding domain	IPR000595	Cyclic nucleotide-binding domain	22	114	1.3E-22
SMART	SM00419	crpmeuga4	IPR012318	Crp-type HTH domain	164	212	6.6E-15
SMART	SM00100	cnmp_10	IPR000595	Cyclic nucleotide-binding domain	3	126	2.5E-27
FunFam	G3DSA:2.60.120.10:FF:000001	cAMP-activated global transcriptional regulator CRP	-	-	3	136	8.2E-62
Gene3D	G3DSA:2.60.120.10	Jelly Rolls	IPR014710	RmlC-like jelly roll fold	11	142	3.2E-37
PANTHER	PTHR24567	CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN	-	-	10	205	2.4E-30
CDD	cd00092	HTH_CRP	-	-	144	206	1.43828E-12
SUPERFAMILY	SSF46785	Winged helix DNA-binding domain	IPR036390	Winged helix DNA-binding domain superfamily	143	211	6.0E-16
CDD	cd00038	CAP_ED	IPR000595	Cyclic nucleotide-binding domain	13	121	4.21591E-31
Pfam	PF13545	Crp-like helix-turn-helix domain	IPR012318	Crp-type HTH domain	146	209	1.5E-12
SUPERFAMILY	SSF51206	cAMP-binding domain-like	IPR018490	Cyclic nucleotide-binding domain superfamily	12	141	1.22E-34

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.