Pseudomonas aeruginosa PAO1, PA0662 (argC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0008800 beta-lactamase activity
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00859
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006526 arginine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00150
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003942 N-acetyl-gamma-glutamyl-phosphate reductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00150
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00859
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008652 cellular amino acid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02774
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0070401 NADP+ binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00150
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046983 protein dimerization activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02774
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00220 Arginine biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-arginine biosynthesis IV (archaebacteria) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01210 2-Oxocarboxylic acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-arginine biosynthesis III (via <i>N</i>-acetyl-L-citrulline) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc GLUTORN-PWY L-ornithine biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc ARGSYNBSUB-PWY L-arginine biosynthesis II (acetyl cycle) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 2 172 1.74E-53
Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain IPR000534 Semialdehyde dehydrogenase, NAD-binding 3 142 3.2E-38
Gene3D G3DSA:3.30.360.10 Dihydrodipicolinate Reductase; domain 2 - - 148 312 4.9E-128
Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 2 338 43.662308
SMART SM00859 Semialdhyde_dh_3 IPR000534 Semialdehyde dehydrogenase, NAD-binding 3 142 8.1E-64
Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain IPR012280 Semialdehyde dehydrogenase, dimerisation domain 159 315 6.7E-17
SUPERFAMILY SSF55347 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain - - 150 312 1.09E-51
NCBIfam TIGR01850 JCVI: N-acetyl-gamma-glutamyl-phosphate reductase IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 2 344 0.0
Gene3D G3DSA:3.40.50.720 - - - 3 330 4.9E-128
FunFam G3DSA:3.30.360.10:FF:000014 N-acetyl-gamma-glutamyl-phosphate reductase - - 148 312 8.4E-52
PANTHER PTHR32338 N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATE REDUCTASE, CHLOROPLASTIC-RELATED-RELATED - - 2 344 9.5E-126

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.