Pseudomonas aeruginosa PAO1, PA0766 (mucD)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0007165	signal transduction	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	21036998	Reviewed by curator
Cellular Component	GO:0042597	periplasmic space	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	21713511	Reviewed by curator
Molecular Function	GO:0004252	serine-type endopeptidase activity	ISS Inferred from Sequence or Structural Similarity Term mapped from: RefSeq:NP_414703.1	ECO:0000250 sequence similarity evidence used in manual assertion	16376476	Reviewed by curator
Biological Process	GO:0006508	proteolysis	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR02037	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005515	protein binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF50156	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0004252	serine-type endopeptidase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR02037	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class Putative enzymes Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae01503	Cationic antimicrobial peptide (CAMP) resistance	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Alginate biosynthesis		ECO:0000037 not_recorded
KEGG	pae02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF13180	PDZ domain	IPR001478	PDZ domain	272	359	2.8E-17
NCBIfam	TIGR02037	JCVI: Do family serine endopeptidase	IPR011782	Peptidase S1C, Do	28	470	0.0
PRINTS	PR00834	HtrA/DegQ protease family signature	IPR001940	Peptidase S1C	224	241	5.9E-53
Pfam	PF13180	PDZ domain	IPR001478	PDZ domain	386	466	1.4E-9
Gene3D	G3DSA:2.30.42.10	-	IPR036034	PDZ superfamily	381	474	1.1E-17
FunFam	G3DSA:2.40.10.120:FF:000007	Periplasmic serine endoprotease DegP-like	-	-	28	263	1.9E-106
PRINTS	PR00834	HtrA/DegQ protease family signature	IPR001940	Peptidase S1C	107	119	5.9E-53
CDD	cd00987	PDZ_serine_protease	-	-	270	359	8.75556E-27
SUPERFAMILY	SSF50494	Trypsin-like serine proteases	IPR009003	Peptidase S1, PA clan	6	279	2.58E-70
PRINTS	PR00834	HtrA/DegQ protease family signature	IPR001940	Peptidase S1C	168	192	5.9E-53
Gene3D	G3DSA:2.40.10.120	-	-	-	27	263	2.1E-85
Gene3D	G3DSA:2.30.42.10	-	IPR036034	PDZ superfamily	268	369	3.4E-28
SMART	SM00228	pdz_new	IPR001478	PDZ domain	270	352	3.9E-15
Pfam	PF02163	Peptidase family M50	IPR008915	Peptidase M50	239	376	4.8E-11
SUPERFAMILY	SSF50156	PDZ domain-like	IPR036034	PDZ superfamily	385	472	4.86E-15
Pfam	PF13365	Trypsin-like peptidase domain	-	-	98	231	3.6E-34
PRINTS	PR00834	HtrA/DegQ protease family signature	IPR001940	Peptidase S1C	310	322	5.9E-53
SMART	SM00228	pdz_new	IPR001478	PDZ domain	384	463	3.7E-11
PRINTS	PR00834	HtrA/DegQ protease family signature	IPR001940	Peptidase S1C	128	148	5.9E-53
PANTHER	PTHR22939	SERINE PROTEASE FAMILY S1C HTRA-RELATED	-	-	23	362	1.1E-101
PRINTS	PR00834	HtrA/DegQ protease family signature	IPR001940	Peptidase S1C	202	219	5.9E-53
FunFam	G3DSA:2.30.42.10:FF:000037	Periplasmic serine endoprotease DegP-like	-	-	268	369	1.5E-34
CDD	cd00987	PDZ_serine_protease	-	-	385	470	9.20473E-18
SUPERFAMILY	SSF50156	PDZ domain-like	IPR036034	PDZ superfamily	252	358	4.05E-23

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.