Pseudomonas aeruginosa PAO1, PA0767 (lepA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003924 GTPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00315
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005525 GTP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03144
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other PAO1 genes in this class
Protein secretion/export apparatus Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR01393 JCVI: translation elongation factor 4 IPR006297 Elongation factor 4 6 598 0.0
PRINTS PR00315 GTP-binding elongation factor signature IPR000795 Translational (tr)-type GTP-binding domain 129 138 8.8E-14
CDD cd03699 EF4_II - - 194 279 2.09068E-41
Hamap MF_00071 Elongation factor 4 [lepA]. IPR006297 Elongation factor 4 1 599 303.511383
PRINTS PR00315 GTP-binding elongation factor signature IPR000795 Translational (tr)-type GTP-binding domain 93 104 8.8E-14
Pfam PF00009 Elongation factor Tu GTP binding domain IPR000795 Translational (tr)-type GTP-binding domain 6 184 1.1E-51
CDD cd03709 lepA_C IPR035654 Elongation factor 4, domain IV 404 482 1.56013E-37
PRINTS PR00315 GTP-binding elongation factor signature IPR000795 Translational (tr)-type GTP-binding domain 77 87 8.8E-14
Pfam PF00679 Elongation factor G C-terminus IPR000640 Elongation factor EFG, domain V-like 402 487 9.0E-19
SUPERFAMILY SSF54980 EF-G C-terminal domain-like IPR035647 EF-G domain III/V-like 295 373 1.47E-18
SUPERFAMILY SSF54980 EF-G C-terminal domain-like IPR035647 EF-G domain III/V-like 403 496 4.65E-24
Gene3D G3DSA:2.40.30.10 Translation factors - - 189 288 7.2E-35
FunFam G3DSA:3.30.70.2570:FF:000001 Translation factor GUF1, mitochondrial - - 482 556 7.1E-36
Pfam PF06421 GTP-binding protein LepA C-terminus IPR013842 GTP-binding protein LepA, C-terminal 490 596 1.2E-50
Gene3D G3DSA:3.30.70.2570 - IPR038363 LepA, C-terminal domain superfamily 482 556 4.2E-33
FunFam G3DSA:3.40.50.300:FF:000078 Elongation factor 4 - - 4 188 4.2E-89
FunFam G3DSA:3.30.70.870:FF:000004 Translation factor GUF1, mitochondrial - - 289 370 2.3E-38
Gene3D G3DSA:3.30.70.240 - - - 371 480 4.3E-34
Pfam PF03144 Elongation factor Tu domain 2 IPR004161 Translation elongation factor EFTu-like, domain 2 208 278 1.9E-10
NCBIfam TIGR00231 JCVI: small GTP-binding protein domain IPR005225 Small GTP-binding protein domain 9 175 1.0E-17
CDD cd01890 LepA - - 8 186 3.2756E-123
CDD cd16260 EF4_III - - 296 371 6.19081E-48
PANTHER PTHR43512 TRANSLATION FACTOR GUF1-RELATED IPR006297 Elongation factor 4 4 597 0.0
FunFam G3DSA:3.30.70.240:FF:000007 Translation factor GUF1, mitochondrial - - 371 480 3.4E-31
Gene3D G3DSA:3.30.70.870 Elongation Factor G (Translational Gtpase), domain 3 - - 289 370 6.8E-38
FunFam G3DSA:2.40.30.10:FF:000015 Translation factor GUF1, mitochondrial - - 189 287 1.3E-34
PRINTS PR00315 GTP-binding elongation factor signature IPR000795 Translational (tr)-type GTP-binding domain 9 22 8.8E-14
PRINTS PR00315 GTP-binding elongation factor signature IPR000795 Translational (tr)-type GTP-binding domain 52 60 8.8E-14
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 5 188 3.4E-61
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 1 235 3.42E-56

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.