Pseudomonas aeruginosa PAO1, PA0768 (lepB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008233 peptidase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 22730125 Reviewed by curator
Biological Process GO:0006465 signal peptide processing
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd06530
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004252 serine-type endopeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd06530
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008236 serine-type peptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00727
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006508 proteolysis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00727
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00727
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Protein secretion/export apparatus Other PAO1 genes in this class
Translation, post-translational modification, degradation Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae03060 Protein export 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae02024 Quorum sensing 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51306 LexA/Signal peptidase IPR036286 LexA/Signal peptidase-like superfamily 77 271 1.44E-64
CDD cd06530 S26_SPase_I IPR019533 Peptidase S26 82 259 3.02595E-25
PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature IPR000223 Peptidase S26A, signal peptidase I 216 235 5.4E-26
NCBIfam TIGR02227 JCVI: signal peptidase I IPR000223 Peptidase S26A, signal peptidase I 64 266 6.8E-49
PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature IPR000223 Peptidase S26A, signal peptidase I 79 95 5.4E-26
Pfam PF10502 Signal peptidase, peptidase S26 IPR019533 Peptidase S26 60 264 8.2E-61
PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature IPR000223 Peptidase S26A, signal peptidase I 143 155 5.4E-26
PANTHER PTHR43390 SIGNAL PEPTIDASE I IPR000223 Peptidase S26A, signal peptidase I 55 265 3.3E-48
Gene3D G3DSA:2.10.109.10 Umud Fragment, subunit A - - 75 280 8.0E-51

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.