Pseudomonas aeruginosa PAO1, PA0810

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0810
Name
Replicon chromosome
Genomic location 887583 - 888284 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249501.1
GI 15596007
Affymetrix PA0810_at
DNASU PaCD00006370
Entrez 882076
GenBank AAG04199.1
INSDC AAG04199.1
NCBI Locus Tag PA0810
protein_id(GenBank) gb|AAG04199.1|AE004516_4|gnl|PseudoCAP|PA0810
TIGR NTL03PA00811
UniParc UPI00000C5166
UniProtKB Acc Q9I5C9
UniProtKB ID Q9I5C9_PSEAE
UniRef100 UniRef100_W0YL66
UniRef50 UniRef50_A6VAG5
UniRef90 UniRef90_A6VAG5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable haloacid dehalogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -6.20
Kyte-Doolittle Hydrophobicity Value -0.134
Molecular Weight (kDa) 26.3
Isoelectric Point (pI) 5.54

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3UMC HYDROLASE 11/13/11 Crystal Structure of the L-2-Haloacid Dehalogenase PA0810 Pseudomonas aeruginosa 2.15 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 158 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000783 (323 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0810

Human Homologs

References

Complete nucleotide sequences and comparison of the structural genes of two 2-haloalkanoic acid dehalogenases from Pseudomonas sp. strain CBS3.
Schneider B, Müller R, Frank R, Lingens F
J Bacteriol 1991 Feb;173(4):1530-5
PubMed ID: 1995594
Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity. Application of an iterative approach to database search.
Koonin EV, Tatusov RL
J Mol Biol 1994 Nov 18;244(1):125-32
PubMed ID: 7966317