Pseudomonas aeruginosa PAO1, PA0838

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0838
Name
Synonym: btuE
Replicon chromosome
Genomic location 913777 - 914259 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249529.1
GI 15596035
Affymetrix PA0838_at
DNASU PaCD00006384
Entrez 879443
GenBank AAG04227.1
INSDC AAG04227.1
NCBI Locus Tag PA0838
protein_id(GenBank) gb|AAG04227.1|AE004518_8|gnl|PseudoCAP|PA0838
TIGR NTL03PA00839
UniParc UPI00000C5181
UniProtKB Acc Q9I5A2
UniProtKB ID Q9I5A2_PSEAE
UniRef100 UniRef100_W0YMQ5
UniRef50 UniRef50_P73824
UniRef90 UniRef90_Q02HZ7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable glutathione peroxidase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.62
Kyte-Doolittle Hydrophobicity Value -0.079
Molecular Weight (kDa) 17.3
Isoelectric Point (pI) 4.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 325 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000806 (529 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0838

Human Homologs

Ensembl 110, assembly GRCh38.p14
glutathione peroxidase 7 [Source:HGNC Symbol;Acc:HGNC:4559]
E-value: 2.8e-28
Percent Identity: 39.0

References

Nucleotide sequence of the btuCED genes involved in vitamin B12 transport in Escherichia coli and homology with components of periplasmic-binding-protein-dependent transport systems.
Friedrich MJ, de Veaux LC, Kadner RJ
J Bacteriol 1986 Sep;167(3):928-34
PubMed ID: 3528129
The carB gene encoding the large subunit of carbamoylphosphate synthetase from Lactococcus lactis is transcribed monocistronically.
Martinussen J, Hammer K
J Bacteriol 1998 Sep;180(17):4380-6
PubMed ID: 9721272