Pseudomonas aeruginosa PAO1, PA0847
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0052621 | diguanylate cyclase activity | Inferred from Direct Assay | ECO:0000005 enzyme assay evidence |
16477007 | Reviewed by curator |
| Molecular Function | GO:0009975 | cyclase activity | |
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| Biological Process | GO:0007165 | signal transduction |
Inferred from Sequence Model
Term mapped from: InterPro:PF00672
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006355 | regulation of transcription, DNA-templated |
Inferred from Sequence Model
Term mapped from: InterPro:PF00989
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0016020 | membrane |
Inferred from Sequence Model
Term mapped from: InterPro:PF00672
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| SMART | SM00304 | HAMP_11 | IPR003660 | HAMP domain | 394 | 446 | 3.2E-7 |
| SMART | SM00267 | duf1_3 | IPR000160 | GGDEF domain | 560 | 731 | 1.9E-63 |
| Gene3D | G3DSA:6.10.340.10 | - | - | - | 364 | 445 | 1.5E-8 |
| FunFam | G3DSA:3.30.70.270:FF:000001 | Diguanylate cyclase domain protein | - | - | 566 | 732 | 6.6E-45 |
| Gene3D | G3DSA:3.30.70.270 | - | IPR043128 | Reverse transcriptase/Diguanylate cyclase domain | 569 | 733 | 6.6E-57 |
| SMART | SM00086 | pac_2 | IPR001610 | PAC motif | 518 | 560 | 8.1E-5 |
| SUPERFAMILY | SSF158472 | HAMP domain-like | - | - | 395 | 443 | 7.98E-5 |
| CDD | cd06225 | HAMP | - | - | 397 | 441 | 3.13593E-5 |
| SUPERFAMILY | SSF55785 | PYP-like sensor domain (PAS domain) | IPR035965 | PAS domain superfamily | 433 | 558 | 5.32E-28 |
| Coils | Coil | Coil | - | - | 427 | 447 | - |
| Pfam | PF05228 | CHASE4 domain | IPR007892 | CHASE4 | 137 | 299 | 4.5E-28 |
| PANTHER | PTHR46663 | DIGUANYLATE CYCLASE DGCT-RELATED | - | - | 1 | 734 | 8.4E-121 |
| SUPERFAMILY | SSF55073 | Nucleotide cyclase | IPR029787 | Nucleotide cyclase | 576 | 731 | 1.49E-46 |
| Gene3D | G3DSA:3.30.450.20 | PAS domain | - | - | 446 | 568 | 8.0E-26 |
| Pfam | PF00672 | HAMP domain | IPR003660 | HAMP domain | 395 | 442 | 9.5E-8 |
| Pfam | PF00989 | PAS fold | IPR013767 | PAS fold | 447 | 557 | 1.2E-15 |
| NCBIfam | TIGR00229 | JCVI: PAS domain S-box protein | IPR000014 | PAS domain | 443 | 567 | 1.3E-22 |
| NCBIfam | TIGR00254 | JCVI: diguanylate cyclase (GGDEF) domain | IPR000160 | GGDEF domain | 569 | 727 | 1.2E-41 |
| CDD | cd00130 | PAS | IPR000014 | PAS domain | 455 | 557 | 1.8594E-17 |
| Pfam | PF00990 | Diguanylate cyclase, GGDEF domain | IPR000160 | GGDEF domain | 571 | 725 | 4.3E-45 |
| CDD | cd01949 | GGDEF | IPR000160 | GGDEF domain | 572 | 729 | 8.52374E-63 |
| SMART | SM00091 | pas_2 | IPR000014 | PAS domain | 446 | 512 | 6.3E-15 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.