Pseudomonas aeruginosa PAO1, PA0856

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0856
Name
Replicon chromosome
Genomic location 935427 - 935975 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249547.1
GI 15596053
Affymetrix PA0856_at
DNASU PaCD00006392
Entrez 879247
GenBank AAG04245.1
INSDC AAG04245.1
NCBI Locus Tag PA0856
protein_id(GenBank) gb|AAG04245.1|AE004520_8|gnl|PseudoCAP|PA0856
TIGR NTL03PA00857
UniParc UPI00000C518F
UniProtKB Acc Q9I585
UniProtKB ID Q9I585_PSEAE
UniRef100 UniRef100_Q9I585
UniRef50 UniRef50_Q9I585
UniRef90 UniRef90_Q9I585

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.23
Kyte-Doolittle Hydrophobicity Value -0.331
Molecular Weight (kDa) 20.0
Isoelectric Point (pI) 10.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2X3O UNKNOWN FUNCTION 01/25/10 Crystal Structure of the Hypothetical Protein PA0856 from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 2.9 X-RAY DIFFRACTION 100.0
3OAO UNKNOWN FUNCTION 08/05/10 Crystal structure of a protein with unknown function from DUF2059 family (PA0856) from PSEUDOMONAS AERUGINOSA at 2.72 A resolution Pseudomonas aeruginosa 2.72 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 35 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000823 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0856

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295