Pseudomonas aeruginosa PAO1, PA0901 (aruE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006520 cellular amino acid metabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0006527 arginine catabolic process
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 16593724 Reviewed by curator
Molecular Function GO:0016788 hydrolase activity, acting on ester bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04952
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019545 arginine catabolic process to succinate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd03855
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0009017 succinylglutamate desuccinylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd03855
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd03855
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019544 arginine catabolic process to glutamate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd03855
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc AST-PWY L-arginine degradation II (AST pathway) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00330 Arginine and proline metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Arginine and proline metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF017020 ASTE IPR016681 Succinylglutamate desuccinylase 1 332 2.9E-117
SUPERFAMILY SSF53187 Zn-dependent exopeptidases - - 6 329 1.69E-76
PANTHER PTHR15162 ASPARTOACYLASE - - 28 327 8.5E-55
Gene3D G3DSA:3.40.630.10 Zn peptidases - - 5 332 9.1E-105
Hamap MF_00767 Succinylglutamate desuccinylase [astE]. IPR016681 Succinylglutamate desuccinylase 1 332 153.935074
FunFam G3DSA:3.40.630.10:FF:000017 Succinylglutamate desuccinylase - - 4 331 0.0
Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family IPR007036 Succinylglutamate desuccinylase/aspartoacylase 49 330 1.1E-80
NCBIfam TIGR03242 JCVI: succinylglutamate desuccinylase IPR016681 Succinylglutamate desuccinylase 6 328 4.8E-115
CDD cd03855 M14_ASTE IPR016681 Succinylglutamate desuccinylase 7 243 3.79137E-114

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.