Pseudomonas aeruginosa PAO1, PA1003 (mvfR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0034762 regulation of transmembrane transport
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
19497948 Reviewed by curator
Biological Process GO:0043902 positive regulation of multi-organism process
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
15686549 Reviewed by curator
Biological Process GO:0051349 positive regulation of lyase activity
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
14739337 Reviewed by curator
Molecular Function GO:0000976 transcription regulatory region sequence-specific DNA binding
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
16735731 Reviewed by curator
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00126
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003700 DNA-binding transcription factor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00126
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class
Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae02024 Quorum sensing 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.190.290:FF:000026 Transcriptional regulator MvfR - - 94 309 0.0
SUPERFAMILY SSF46785 Winged helix DNA-binding domain IPR036390 Winged helix DNA-binding domain superfamily 3 78 7.07E-13
Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family IPR000847 Transcription regulator HTH, LysR 6 64 1.6E-10
Pfam PF03466 LysR substrate binding domain IPR005119 LysR, substrate-binding 139 292 2.5E-14
CDD cd05466 PBP2_LTTR_substrate - - 102 286 1.81721E-14
Gene3D G3DSA:1.10.10.10 - IPR036388 Winged helix-like DNA-binding domain superfamily 4 81 1.7E-14
PANTHER PTHR30579 TRANSCRIPTIONAL REGULATOR - - 1 301 2.7E-70
SUPERFAMILY SSF53850 Periplasmic binding protein-like II - - 140 296 1.16E-18
Gene3D G3DSA:3.40.190.290 - - - 94 309 1.5E-102

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.