Pseudomonas aeruginosa PAO1, PA1032 (quiP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
16461666 Reviewed by curator
Molecular Function GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.439.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0017000 antibiotic biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR34218
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR34218
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other PAO1 genes in this class
Antibiotic resistance and susceptibility Other PAO1 genes in this class
Carbon compound catabolism Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) IPR029055 Nucleophile aminohydrolases, N-terminal 52 840 0.0
PIRSF PIRSF001227 Pen_acylase IPR014395 Penicillin/GL-7-ACA/AHL acylase 17 842 0.0
CDD cd03747 Ntn_PGA_like - - 265 563 1.22542E-98
Pfam PF01804 Penicillin amidase IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase 56 833 0.0
Gene3D G3DSA:3.60.20.10 Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 IPR029055 Nucleophile aminohydrolases, N-terminal 265 823 0.0
Gene3D G3DSA:1.10.439.10 Penicillin Amidohydrolase, domain 1 IPR023343 Penicillin amidase type, domain 1 31 188 1.6E-44
Gene3D G3DSA:2.30.120.10 - IPR043146 Penicillin amidase type, N-terminal domain, B-knob 337 418 0.0
PANTHER PTHR34218 PEPTIDASE S45 PENICILLIN AMIDASE IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase 6 842 0.0
Gene3D G3DSA:1.10.1400.10 - IPR043147 Penicillin amidase type, A-knob 566 718 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.