Pseudomonas aeruginosa PAO1, PA1099 (fleR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006355 regulation of transcription, DNA-templated
IDA
Inferred from Direct Assay
ECO:0000002
direct assay evidence
Biological Process GO:2000155 positive regulation of cilium-dependent cell motility
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
7591148 Reviewed by curator
Biological Process GO:1900191 negative regulation of single-species biofilm formation
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
15231779 Reviewed by curator
Biological Process GO:0045785 positive regulation of cell adhesion
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
7591148 Reviewed by curator
Molecular Function GO:0000156 phosphorelay response regulator activity
ISA
Inferred from Sequence Alignment
Term mapped from: PseudoCAP:PAK_04272
ECO:0000247
sequence alignment evidence used in manual assertion
7591148 Reviewed by curator
Molecular Function GO:0000156 phosphorelay response regulator activity
ISS
Inferred from Sequence or Structural Similarity
ECO:0000250
sequence similarity evidence used in manual assertion
7591148 Reviewed by curator
Molecular Function GO:0008134 transcription factor binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00448
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02954
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class
Motility & Attachment Other PAO1 genes in this class
Transcriptional regulators Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Two-component System ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 4 174 2.85E-41
Gene3D G3DSA:3.40.50.2300 - - - 2 126 1.1E-32
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 442 462 7.0E-6
Pfam PF02954 Bacterial regulatory protein, Fis family IPR002197 DNA binding HTH domain, Fis-type 419 458 4.7E-13
Gene3D G3DSA:1.10.8.60 - - - 302 375 3.2E-22
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 150 293 7.1E-13
Gene3D G3DSA:1.10.10.60 - - - 402 462 2.0E-9
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 425 442 7.0E-6
FunFam G3DSA:1.10.10.60:FF:000461 Sigma-54-dependent Fis family transcriptional regulator - - 402 462 6.1E-38
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 5 114 2.7E-25
FunFam G3DSA:3.40.50.300:FF:000006 DNA-binding transcriptional regulator NtrC - - 125 300 1.0E-74
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 3 114 1.3E-33
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 343 458 1.34E-11
PANTHER PTHR32071 TRANSCRIPTIONAL REGULATORY PROTEIN - - 1 459 1.6E-130
FunFam G3DSA:3.40.50.2300:FF:000018 DNA-binding transcriptional regulator NtrC - - 1 127 8.5E-40
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 127 301 4.9E-64
Pfam PF00158 Sigma-54 interaction domain IPR002078 RNA polymerase sigma factor 54 interaction domain 135 296 5.1E-67
CDD cd00009 AAA - - 131 292 2.69402E-23
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 132 371 1.62E-70

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.