Pseudomonas aeruginosa PAO1, PA1107 (roeA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0045226 extracellular polysaccharide biosynthetic process
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
20978535 Reviewed by curator
Molecular Function GO:0052621 diguanylate cyclase activity
IDA
Inferred from Direct Assay
ECO:0000005
enzyme assay evidence
16477007 Reviewed by curator
Molecular Function GO:0052621 diguanylate cyclase activity
IDA
Inferred from Direct Assay
ECO:0000005
enzyme assay evidence
20978535 Reviewed by curator

Functional Classifications Manually Assigned by PseudoCAP

Motility & Attachment Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00990 Diguanylate cyclase, GGDEF domain IPR000160 GGDEF domain 227 384 1.9E-46
CDD cd01949 GGDEF IPR000160 GGDEF domain 228 385 3.18999E-53
FunFam G3DSA:3.30.70.270:FF:000001 Diguanylate cyclase domain protein - - 221 390 3.2E-53
NCBIfam TIGR00254 JCVI: diguanylate cyclase (GGDEF) domain IPR000160 GGDEF domain 222 387 4.3E-52
PANTHER PTHR45138 REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM - - 180 387 1.7E-73
Coils Coil Coil - - 198 225 -
Gene3D G3DSA:3.30.70.270 - IPR043128 Reverse transcriptase/Diguanylate cyclase domain 211 389 1.7E-61
SUPERFAMILY SSF55073 Nucleotide cyclase IPR029787 Nucleotide cyclase 231 387 1.8E-50
SMART SM00267 duf1_3 IPR000160 GGDEF domain 215 388 3.1E-66

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.