Pseudomonas aeruginosa PAO1, PA1173 (napB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1173
Name
napB
Replicon chromosome
Genomic location 1272807 - 1273298 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249864.1
GI 15596370
Affymetrix PA1173_napB_at
DNASU PaCD00006540
Entrez 878319
GenBank AAG04562.1
INSDC AAG04562.1
NCBI Locus Tag PA1173
protein_id(GenBank) gb|AAG04562.1|AE004547_8|gnl|PseudoCAP|PA1173
TIGR NTL03PA01174
UniParc UPI00000C528B
UniProtKB Acc Q9I4G4
UniProtKB ID Q9I4G4_PSEAE
UniRef100 UniRef100_Q9I4G4
UniRef50 UniRef50_Q9I4G4
UniRef90 UniRef90_Q9I4G4

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome c-type protein NapB precursor
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.83
Kyte-Doolittle Hydrophobicity Value -0.480
Molecular Weight (kDa) 17.9
Isoelectric Point (pI) 8.33

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Periplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 80 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001131 (348 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1173
Search term: napB

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Structure and function of a periplasmic nitrate reductase in Alcaligenes eutrophus H16.
Siddiqui RA, Warnecke-Eberz U, Hengsberger A, Schneider B, Kostka S, Friedrich B
J Bacteriol 1993 Sep;175(18):5867-76
PubMed ID: 8376334