Pseudomonas aeruginosa PAO1, PA1194

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1194
Name
Replicon chromosome
Genomic location 1294811 - 1296229 (- strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249885.1
GI 15596391
Affymetrix PA1194_at
Entrez 879327
GenBank AAG04583.1
INSDC AAG04583.1
NCBI Locus Tag PA1194
protein_id(GenBank) gb|AAG04583.1|AE004549_10|gnl|PseudoCAP|PA1194
TIGR NTL03PA01195
UniParc UPI00000C529E
UniProtKB Acc Q9I4E4
UniProtKB ID Q9I4E4_PSEAE
UniRef100 UniRef100_W0YNZ1
UniRef50 UniRef50_W0WKI1
UniRef90 UniRef90_W0WKI1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable amino acid permease
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 5.26
Kyte-Doolittle Hydrophobicity Value 0.890
Molecular Weight (kDa) 49.9
Isoelectric Point (pI) 8.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 173 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001152 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1194

Human Homologs

Ensembl 110, assembly GRCh38.p14
solute carrier family 7 member 8 [Source:HGNC Symbol;Acc:HGNC:11066]
E-value: 1.1e-05
Percent Identity: 32.4

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
The arc operon for anaerobic arginine catabolism in Pseudomonas aeruginosa contains an additional gene, arcD, encoding a membrane protein.
Lüthi E, Baur H, Gamper M, Brunner F, Villeval D, Mercenier A, Haas D
Gene 1990 Mar 1;87(1):37-43
PubMed ID: 2158926
The arcABDC gene cluster, encoding the arginine deiminase pathway of Bacillus licheniformis, and its activation by the arginine repressor argR.
Maghnouj A, de Sousa Cabral TF, Stalon V, Vander Wauven C
J Bacteriol 1998 Dec;180(24):6468-75
PubMed ID: 9851988