Pseudomonas aeruginosa PAO1, PA1278 (cobP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0051188 obsolete cofactor biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009236 cobalamin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006135
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043752 adenosylcobinamide kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006135
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006135
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Cobalamin biosynthesis ECO:0000037
not_recorded
KEGG pae00860 Porphyrin and chlorophyll metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Porphyrin and chlorophyll metabolism ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc COBALSYN-PWY adenosylcobalamin salvage from cobinamide I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF006135 CobU IPR003203 Bifunctional adenosylcobalamin biosynthesis protein CobU/CobP 1 171 5.8E-52
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 3 169 3.7E-57
FunFam G3DSA:3.40.50.300:FF:001825 Bifunctional adenosylcobalamin biosynthesis protein - - 2 169 6.9E-88
PANTHER PTHR34848 - IPR003203 Bifunctional adenosylcobalamin biosynthesis protein CobU/CobP 1 169 1.7E-70
Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase IPR003203 Bifunctional adenosylcobalamin biosynthesis protein CobU/CobP 4 168 1.1E-59
CDD cd00544 CobU IPR003203 Bifunctional adenosylcobalamin biosynthesis protein CobU/CobP 4 166 3.05523E-63
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 4 169 1.97E-52

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.