Pseudomonas aeruginosa PAO1, PA1286

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1286
Name
Replicon chromosome
Genomic location 1397254 - 1398453 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249977.1
GI 15596483
Affymetrix PA1286_at
Entrez 881763
GenBank AAG04675.1
INSDC AAG04675.1
NCBI Locus Tag PA1286
protein_id(GenBank) gb|AAG04675.1|AE004558_4|gnl|PseudoCAP|PA1286
TIGR NTL03PA01287
UniParc UPI00000C52EE
UniProtKB Acc Q9I458
UniProtKB ID Q9I458_PSEAE
UniRef100 UniRef100_V6AIZ3
UniRef50 UniRef50_Q885W3
UniRef90 UniRef90_V6AIZ3

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 8.36
Kyte-Doolittle Hydrophobicity Value 0.939
Molecular Weight (kDa) 41.9
Isoelectric Point (pI) 9.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 239 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001231 (526 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1286

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Lactic acid efflux from white skeletal muscle is catalyzed by the monocarboxylate transporter isoform MCT3.
Wilson MC, Jackson VN, Heddle C, Price NT, Pilegaard H, Juel C, Bonen A, Montgomery I, Hutter OF, Halestrap AP
J Biol Chem 1998 Jun 26;273(26):15920-6
PubMed ID: 9632638