Pseudomonas aeruginosa PAO1, PA1297

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1297
Name
Replicon chromosome
Genomic location 1407951 - 1408931 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249988.1
GI 15596494
Affymetrix PA1297_at
Entrez 881510
GenBank AAG04686.1
INSDC AAG04686.1
NCBI Locus Tag PA1297
protein_id(GenBank) gb|AAG04686.1|AE004559_5|gnl|PseudoCAP|PA1297
TIGR NTL03PA01298
UniParc UPI00000C52F8
UniProtKB Acc Q9I447
UniProtKB ID Q9I447_PSEAE
UniRef100 UniRef100_Q9I447
UniRef50 UniRef50_Q0KF00
UniRef90 UniRef90_A0A077JYL1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable metal transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 1.56
Kyte-Doolittle Hydrophobicity Value 0.200
Molecular Weight (kDa) 35.8
Isoelectric Point (pI) 7.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 405 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000388 (818 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1297

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
CzcR and CzcD, gene products affecting regulation of resistance to cobalt, zinc, and cadmium (czc system) in Alcaligenes eutrophus.
Nies DH
J Bacteriol 1992 Dec;174(24):8102-10
PubMed ID: 1459958
Molecular characterization of a chromosomal determinant conferring resistance to zinc and cobalt ions in Staphylococcus aureus.
Xiong A, Jayaswal RK
J Bacteriol 1998 Aug;180(16):4024-9
PubMed ID: 9696746