Pseudomonas aeruginosa PAO1, PA1300 (hxuI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1300
Name
hxuI
Replicon chromosome
Genomic location 1409949 - 1410476 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_249991.1
GI 15596497
Affymetrix PA1300_at
DNASU PaCD00006598
Entrez 881504
GenBank AAG04689.1
INSDC AAG04689.1
NCBI Locus Tag PA1300
protein_id(GenBank) gb|AAG04689.1|AE004559_8|gnl|PseudoCAP|PA1300
TIGR NTL03PA01301
UniParc UPI00000C52FB
UniProtKB Acc Q9I444
UniProtKB ID Q9I444_PSEAE
UniRef100 UniRef100_W0YNZ3
UniRef50 UniRef50_Q4KGY1
UniRef90 UniRef90_A6V8R0

Product

Feature Type CDS
Coding Frame 1
Product Name
HxuI
Product Name Confidence: Class 1
Synonyms ECF sigma factor
probable sigma-70 factor, ECF subfamily
ECF sigma factor HxuI
Evidence for Translation
Charge (pH 7) 3.89
Kyte-Doolittle Hydrophobicity Value -0.621
Molecular Weight (kDa) 19.8
Isoelectric Point (pI) 9.31

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 350 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001243 (391 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1300
Search term: hxuI
Search term: HxuI

Human Homologs

References

Characterization of five novel Pseudomonas aeruginosa cell-surface signalling systems.
Llamas MA, Mooij MJ, Sparrius M, Vandenbroucke-Grauls CM, Ratledge C, Bitter W
Mol Microbiol 2008 Jan;67(2):458-72
PubMed ID: 18086184
Pseudomonas aeruginosa possesses three distinct systems for sensing and using the host molecule haem.
Otero-Asman JR, García-García AI, Civantos C, Quesada JM, Llamas MA
Environ Microbiol 2019 Dec;21(12):4629-4647
PubMed ID: 31390127