Pseudomonas aeruginosa PAO1, PA1311 (phnX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0019700 organic phosphonate catabolic process
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 9332393 Reviewed by curator
Molecular Function GO:0050194 phosphonoacetaldehyde hydrolase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 9332393 Reviewed by curator
Molecular Function GO:0050194 phosphonoacetaldehyde hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01375
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019700 organic phosphonate catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01375
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00440 Phosphonate and phosphinate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PHOSPHONOTASE-PWY 2-aminoethylphosphonate degradation I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR01422 JCVI: phosphonoacetaldehyde hydrolase IPR006323 Phosphonoacetaldehyde hydrolase 9 259 3.3E-112
FunFam G3DSA:1.10.150.240:FF:000006 Phosphonoacetaldehyde hydrolase - - 27 104 5.3E-38
SUPERFAMILY SSF56784 HAD-like IPR036412 HAD-like superfamily 10 262 3.25E-57
Gene3D G3DSA:3.40.50.1000 - IPR023214 HAD superfamily 11 269 5.0E-96
Gene3D G3DSA:1.10.150.240 Putative phosphatase; domain 2 IPR023198 Phosphoglycolate phosphatase-like, domain 2 27 104 5.0E-96
PANTHER PTHR43434 PHOSPHOGLYCOLATE PHOSPHATASE - - 10 257 4.1E-31
SFLD SFLDF00038 phosphonoacetaldehyde hydrolase - - 1 272 0.0
Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. IPR006323 Phosphonoacetaldehyde hydrolase 1 275 142.689911
SFLD SFLDG01129 C1.5: HAD, Beta-PGM, Phosphatase Like - - 1 272 0.0
NCBIfam TIGR01509 JCVI: HAD-IA family hydrolase IPR006439 HAD hydrolase, subfamily IA 81 206 1.4E-10
Pfam PF00702 haloacid dehalogenase-like hydrolase - - 14 201 7.0E-7
CDD cd02586 HAD_PHN IPR006323 Phosphonoacetaldehyde hydrolase 9 250 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.