Pseudomonas aeruginosa PAO1, PA1455 (fliA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:2000147 positive regulation of cell motility
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
1560774 Reviewed by curator
Biological Process GO:0006355 regulation of transcription, DNA-templated
IDA
Inferred from Direct Assay
ECO:0000002
direct assay evidence
Molecular Function GO:0016987 sigma factor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02479
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02479
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003700 DNA-binding transcription factor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02937
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006352 DNA-templated transcription, initiation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02937
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003899 DNA-directed 5'-3' RNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02479
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02937
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF04539 Sigma-70 region 3 IPR007624 RNA polymerase sigma-70 region 3 103 166 3.1E-9
SUPERFAMILY SSF88659 Sigma3 and sigma4 domains of RNA polymerase sigma factors IPR013324 RNA polymerase sigma factor, region 3/4-like 96 163 9.59E-13
NCBIfam TIGR02937 JCVI: sigma-70 family RNA polymerase sigma factor IPR014284 RNA polymerase sigma-70 like domain 19 241 1.3E-33
NCBIfam TIGR02479 JCVI: FliA/WhiG family RNA polymerase sigma factor IPR012845 RNA polymerase sigma factor, FliA/WhiG 22 241 5.2E-82
SUPERFAMILY SSF88659 Sigma3 and sigma4 domains of RNA polymerase sigma factors IPR013324 RNA polymerase sigma factor, region 3/4-like 163 244 1.44E-20
PRINTS PR00046 Major sigma-70 factor signature IPR000943 RNA polymerase sigma-70 49 62 2.3E-11
PRINTS PR00046 Major sigma-70 factor signature IPR000943 RNA polymerase sigma-70 194 206 2.3E-11
Gene3D G3DSA:1.20.140.160 - - - 93 243 1.0E-43
PRINTS PR00046 Major sigma-70 factor signature IPR000943 RNA polymerase sigma-70 226 237 2.3E-11
CDD cd06171 Sigma70_r4 - - 184 238 3.54711E-13
PRINTS PR00046 Major sigma-70 factor signature IPR000943 RNA polymerase sigma-70 211 226 2.3E-11
PANTHER PTHR30385 SIGMA FACTOR F FLAGELLAR - - 14 245 5.1E-50
Gene3D G3DSA:1.10.1740.10 - - - 6 91 5.8E-26
SUPERFAMILY SSF88946 Sigma2 domain of RNA polymerase sigma factors IPR013325 RNA polymerase sigma factor, region 2 10 94 4.97E-26
FunFam G3DSA:1.20.140.160:FF:000001 RNA polymerase sigma factor FliA - - 93 243 2.5E-71
FunFam G3DSA:1.10.1740.10:FF:000002 RNA polymerase sigma factor FliA - - 7 91 1.1E-40
Pfam PF04542 Sigma-70 region 2 IPR007627 RNA polymerase sigma-70 region 2 22 94 5.0E-20
Pfam PF04545 Sigma-70, region 4 IPR007630 RNA polymerase sigma-70 region 4 190 239 5.8E-19
Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. IPR028617 RNA polymerase sigma factor FliA 8 244 68.11409
PIRSF PIRSF000770 SigK_SigE IPR000943 RNA polymerase sigma-70 1 246 8.5E-36

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.