Pseudomonas aeruginosa PAO1, PA1456 (cheY)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1456
Name
cheY
Replicon chromosome
Genomic location 1585640 - 1586014 (+ strand)

Cross-References

RefSeq NP_250147.1
GI 15596653
Affymetrix PA1456_cheY_at
DNASU PaCD00006667
Entrez 882097
GenBank AAG04845.1
NCBI Locus Tag PA1456
protein_id(GenBank) gb|AAG04845.1|AE004575_4|gnl|PseudoCAP|PA1456
TIGR NTL03PA01457
UniProtKB Acc Q51455
UniProtKB ID CHEY_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component response regulator CheY
Product Name Confidence: Class 1
Synonyms regulatory component of sensory transduction system for chemotaxis
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.53
Kyte-Doolittle Hydrophobicity Value -0.035
Molecular Weight (kDa) 13.9
Isoelectric Point (pI) 6.54

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 624 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001371 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1456
Search term: cheY

Human Homologs

References

The fliA (rpoF) gene of Pseudomonas aeruginosa encodes an alternative sigma factor required for flagellin synthesis.
Starnbach MN, Lory S
Mol Microbiol 1992 Feb;6(4):459-69
PubMed ID: 1560774
Isolation and characterization of chemotaxis mutants and genes of Pseudomonas aeruginosa.
Masduki A, Nakamura J, Ohga T, Umezaki R, Kato J, Ohtake H
J Bacteriol 1995 Feb;177(4):948-52
PubMed ID: 7860605