Pseudomonas aeruginosa PAO1, PA2491 (mexS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0034763 negative regulation of transmembrane transport
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
15687188 Reviewed by curator
Biological Process GO:1900377 negative regulation of secondary metabolite biosynthetic process
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
21075931 Reviewed by curator
Biological Process GO:0050709 negative regulation of protein secretion
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
21075931 Reviewed by curator
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00829
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class
Putative enzymes Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00829 PKS_ER_names_mod IPR020843 Polyketide synthase, enoylreductase domain 11 335 2.6E-13
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 119 274 7.43E-33
SUPERFAMILY SSF50129 GroES-like IPR011032 GroES-like superfamily 3 151 2.65E-28
Pfam PF13602 Zinc-binding dehydrogenase - - 189 335 1.5E-17
PANTHER PTHR43677 SHORT-CHAIN DEHYDROGENASE/REDUCTASE - - 5 336 1.2E-55
Gene3D G3DSA:3.40.50.720 - - - 126 273 2.4E-73
Pfam PF08240 Alcohol dehydrogenase GroES-like domain IPR013154 Alcohol dehydrogenase-like, N-terminal 29 90 1.1E-7
Gene3D G3DSA:3.90.180.10 - - - 13 335 2.4E-73
CDD cd08268 MDR2 - - 2 337 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.