Pseudomonas aeruginosa PAO1, PA2493 (mexE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0042910 xenobiotic transmembrane transporter activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 9044268 Reviewed by curator
Biological Process GO:0046677 response to antibiotic
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0022857 transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Antibiotic resistance and susceptibility Other PAO1 genes in this class
Transport of small molecules Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Coils Coil Coil - - 104 124 -
FunFam G3DSA:2.40.30.170:FF:000011 Efflux RND transporter periplasmic adaptor subunit - - 204 280 5.1E-39
PANTHER PTHR30158 ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER - - 3 381 5.8E-130
Gene3D G3DSA:1.10.287.470 Helix hairpin bin - - 98 171 7.3E-67
Gene3D G3DSA:2.40.420.20 - - - 281 372 1.4E-18
MobiDBLite mobidb-lite consensus disorder prediction - - 389 414 -
Gene3D G3DSA:2.40.30.170 - - - 57 280 7.3E-67
NCBIfam TIGR01730 JCVI: efflux RND transporter periplasmic adaptor subunit IPR006143 RND efflux pump, membrane fusion protein 39 371 5.4E-80
FunFam G3DSA:2.40.420.20:FF:000001 Efflux RND transporter periplasmic adaptor subunit - - 281 372 1.1E-27
Coils Coil Coil - - 149 169 -
Gene3D G3DSA:2.40.50.100 - - - 63 206 7.3E-67
Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain 65 290 1.2E-15
SUPERFAMILY SSF111369 HlyD-like secretion proteins - - 53 294 9.94E-71

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.