Pseudomonas aeruginosa PAO1, PA3134 (gltX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004828 serine-tRNA ligase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0044267 cellular protein metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006536 glutamate metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00987
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006424 glutamyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00022
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004818 glutamate-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00022
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00808
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00987
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00987
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000049 tRNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48163
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0043039 tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00987
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00860 Porphyrin and chlorophyll metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Porphyrin and chlorophyll metabolism ECO:0000037
not_recorded
PseudoCyc PWY-5188 tetrapyrrole biosynthesis I (from glutamate) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc TRNA-CHARGING-PWY tRNA charging 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc P381-PWY adenosylcobalamin biosynthesis II (late cobalt incorporation) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Aminoacyl-tRNA biosynthesis ECO:0000037
not_recorded
PseudoCAP Glutamate metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 4 308 1.42E-110
PANTHER PTHR43311 GLUTAMATE--TRNA LIGASE - - 3 473 0.0
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 1 329 0.0
Pfam PF19269 Anticodon binding domain IPR045462 Aminoacyl-tRNA synthetase, class I, anticodon-binding 333 471 8.3E-31
FunFam G3DSA:3.40.50.620:FF:000045 Glutamate--tRNA ligase, mitochondrial - - 1 329 0.0
Gene3D G3DSA:1.10.10.350 - IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 371 494 2.8E-33
PRINTS PR00987 Glutamyl-tRNA synthetase signature IPR000924 Glutamyl/glutaminyl-tRNA synthetase 21 32 1.3E-21
PRINTS PR00987 Glutamyl-tRNA synthetase signature IPR000924 Glutamyl/glutaminyl-tRNA synthetase 36 49 1.3E-21
PRINTS PR00987 Glutamyl-tRNA synthetase signature IPR000924 Glutamyl/glutaminyl-tRNA synthetase 193 203 1.3E-21
PRINTS PR00987 Glutamyl-tRNA synthetase signature IPR000924 Glutamyl/glutaminyl-tRNA synthetase 209 217 1.3E-21
Hamap MF_00022 Glutamate--tRNA ligase [gltX]. IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial 3 471 30.006924
FunFam G3DSA:1.10.10.350:FF:000007 Glutamate--tRNA ligase - - 371 475 6.1E-52
CDD cd00808 GluRS_core IPR033910 Glutamyl-tRNA synthetase 3 328 0.0
Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain 4 320 1.0E-109
NCBIfam TIGR00464 JCVI: glutamate--tRNA ligase IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial 3 470 0.0
PRINTS PR00987 Glutamyl-tRNA synthetase signature IPR000924 Glutamyl/glutaminyl-tRNA synthetase 7 19 1.3E-21
SUPERFAMILY SSF48163 An anticodon-binding domain of class I aminoacyl-tRNA synthetases IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily 314 472 7.59E-34

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.