Pseudomonas aeruginosa PAO1, PA3149 (wbpH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3149
Name
wbpH
Replicon chromosome
Genomic location 3532812 - 3533933 (- strand)
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_251839.1
GI 15598345
Affymetrix PA3149_wbpH_at
Entrez 882607
GenBank AAG06537.1
INSDC AAG06537.1
NCBI Locus Tag PA3149
protein_id(GenBank) gb|AAG06537.1|AE004738_11|gnl|PseudoCAP|PA3149
TIGR NTL03PA03149
UniParc UPI00000D4285
UniProtKB Acc G3XD85
UniProtKB ID G3XD85_PSEAE
UniRef100 UniRef100_U9IR13
UniRef50 UniRef50_V5RAX1
UniRef90 UniRef90_Q8KIR8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable glycosyltransferase WbpH
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 8.68
Kyte-Doolittle Hydrophobicity Value -0.209
Molecular Weight (kDa) 41.9
Isoelectric Point (pI) 8.83

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0085
Category LPS O-antigen (P. aeruginosa)
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 251 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001311 (2094 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3149
Search term: wbpH

Human Homologs

References

Molecular characterization of the Pseudomonas aeruginosa serotype O5 (PAO1) B-band lipopolysaccharide gene cluster.
Burrows LL, Charter DF, Lam JS
Mol Microbiol 1996 Nov;22(3):481-95
PubMed ID: 8939432