Pseudomonas aeruginosa PAO1, PA3150 (wbpG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3150
Name
wbpG
Replicon chromosome
Genomic location 3533948 - 3535081 (- strand)

Cross-References

RefSeq NP_251840.1
GI 15598346
Affymetrix PA3150_wbpG_at
Entrez 882581
GenBank AAG06538.1
NCBI Locus Tag PA3150
protein_id(GenBank) gb|AAG06538.1|AE004738_12|gnl|PseudoCAP|PA3150
TIGR NTL03PA03150
UniProtKB Acc Q9HZ78
UniProtKB ID Q9HZ78_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
LPS biosynthesis protein WbpG
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (43.50 kDa, PMID:21751344)
Charge (pH 7) 5.67
Kyte-Doolittle Hydrophobicity Value -0.362
Molecular Weight (kDa) 43.5
Isoelectric Point (pI) 8.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Vesicle Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0085
Category LPS O-antigen (P. aeruginosa)
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 59 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005135 (52 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3150
Search term: wbpG

Human Homologs

References

Molecular characterization of the Pseudomonas aeruginosa serotype O5 (PAO1) B-band lipopolysaccharide gene cluster.
Burrows LL, Charter DF, Lam JS
Mol Microbiol 1996 Nov;22(3):481-95
PubMed ID: 8939432
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344