Pseudomonas aeruginosa PAO1, PA5394 (cls)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008808 cardiolipin synthase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 1663113 Reviewed by curator
Biological Process GO:0032049 cardiolipin biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 353047 Reviewed by curator
Biological Process GO:0032049 cardiolipin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR04265
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00155
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008808 cardiolipin synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR04265
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016780 phosphotransferase activity, for other substituted phosphate groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR04265
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Fatty acid and phospholipid metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PHOSLIPSYN-PWY superpathway of phospholipid biosynthesis I (bacteria) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc PWY-5668 cardiolipin biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00564 Glycerophospholipid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd09155 PLDc_PaCLS_like_1 - - 137 292 2.05342E-90
Gene3D G3DSA:3.30.870.10 Endonuclease Chain A - - 123 301 3.6E-44
SUPERFAMILY SSF56024 Phospholipase D/nuclease - - 117 319 9.42E-51
PANTHER PTHR21248 CARDIOLIPIN SYNTHASE - - 41 490 4.7E-104
Gene3D G3DSA:3.30.870.10 Endonuclease Chain A - - 313 461 4.9E-27
Hamap MF_00190 Cardiolipin synthase A [clsA]. IPR030840 Cardiolipin synthase A 13 490 45.89402
FunFam G3DSA:3.30.870.10:FF:000014 Cardiolipin synthase - - 124 308 1.4E-72
CDD cd09161 PLDc_PaCLS_like_2 - - 315 490 8.35852E-108
SMART SM00155 pld_4 IPR001736 Phospholipase D/Transphosphatidylase 229 256 1.7E-4
SMART SM00155 pld_4 IPR001736 Phospholipase D/Transphosphatidylase 403 430 3.1E-6
Pfam PF13091 PLD-like domain IPR025202 Phospholipase D-like domain 331 456 2.7E-27
SUPERFAMILY SSF56024 Phospholipase D/nuclease - - 281 469 5.16E-47
NCBIfam TIGR04265 JCVI: cardiolipin synthase IPR022924 Cardiolipin synthase 25 490 1.4E-109
FunFam G3DSA:3.30.870.10:FF:000021 Cardiolipin synthase - - 313 462 1.0E-71

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.