Pseudomonas aeruginosa PAO1, PA5429 (aspA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006807 nitrogen compound metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006522 alanine metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0003994 aconitate hydratase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006531 aspartate metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006531 aspartate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00839
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016829 lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF10415
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48557
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008797 aspartate ammonia-lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00839
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006099 tricarboxylic acid cycle
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF10415
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Nitrogen metabolism ECO:0000037
not_recorded
PseudoCyc ASPASN-PWY superpathway of L-aspartate and L-asparagine biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Alanine and Aspartate metabolism ECO:0000037
not_recorded
PseudoCyc GLUTDEG-PWY L-glutamate degradation II 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.10.40.30 - - - 413 468 2.9E-17
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 276 303 1.9E-28
Gene3D G3DSA:1.20.200.10 Fumarase/aspartase (Central domain) - - 144 412 2.6E-80
SUPERFAMILY SSF48557 L-aspartase-like IPR008948 L-Aspartase-like 7 465 0.0
PANTHER PTHR42696 ASPARTATE AMMONIA-LYASE - - 7 470 0.0
Gene3D G3DSA:1.10.275.10 - IPR024083 Fumarase/histidase, N-terminal 8 143 5.8E-53
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 184 202 1.9E-28
FunFam G3DSA:1.10.40.30:FF:000002 Fumarate hydratase class II - - 413 468 1.8E-17
CDD cd01357 Aspartase - - 8 459 0.0
FunFam G3DSA:1.10.275.10:FF:000001 Fumarate hydratase, mitochondrial - - 8 143 1.3E-52
Pfam PF00206 Lyase IPR022761 Fumarate lyase, N-terminal 15 347 4.2E-98
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 322 338 1.9E-28
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 139 157 1.9E-28
NCBIfam TIGR00839 JCVI: aspartate ammonia-lyase IPR004708 Aspartate ammonia-lyase 8 467 0.0
Pfam PF10415 Fumarase C C-terminus IPR018951 Fumarase C, C-terminal 413 465 7.5E-20
FunFam G3DSA:1.20.200.10:FF:000001 Fumarate hydratase, mitochondrial - - 144 411 2.3E-112

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.