Pseudomonas aeruginosa PAO1, PA5434 (mtr)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA5434
Name
mtr
Replicon chromosome
Genomic location 6115059 - 6116312 (- strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_254121.1
GI 15600627
Affymetrix PA5434_mtr_at
Entrez 877727
GenBank AAG08819.1
NCBI Locus Tag PA5434
protein_id(GenBank) gb|AAG08819.1|AE004956_3|gnl|PseudoCAP|PA5434
TIGR NTL03PA05435
UniProtKB Acc Q9HTD2
UniProtKB ID Q9HTD2_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
tryptophan permease
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 10.09
Kyte-Doolittle Hydrophobicity Value 0.734
Molecular Weight (kDa) 44.7
Isoelectric Point (pI) 9.75

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 64 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004984 (310 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5434
Search term: mtr

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Cloning, nucleotide sequence, and characterization of mtr, the structural gene for a tryptophan-specific permease of Escherichia coli K-12.
Heatwole VM, Somerville RL
J Bacteriol 1991 Jan;173(1):108-15
PubMed ID: 1987112
The tryptophan-specific permease gene, mtr, is differentially regulated by the tryptophan and tyrosine repressors in Escherichia coli K-12.
Heatwole VM, Somerville RL
J Bacteriol 1991 Jun;173(11):3601-4
PubMed ID: 1904443